RTX 4090 runs Pathologic 2 at approximately ~125 FPS at 1080p High settings — verdict: SMOOTH. At 1440p: ~125 FPS (SMOOTH). At 4K: ~83 FPS (SMOOTH).
The RTX 4090 delivers ~125 FPS in Pathologic 2 at 1440P High settings — exceeding the 60 FPS smooth-play threshold by 65 FPS. This GPU is a strong match for high-refresh-rate monitors on this title. No upgrade needed.
Performance Optimizer
Live SimulationFrequently asked questions — RTX 4090 & Pathologic 2
Can I run Pathologic 2 on RTX 4090?
Yes. The RTX 4090 delivers approximately 125 FPS in Pathologic 2 at 1080p High settings. This exceeds the 60 FPS smooth-play threshold — gameplay is fluid without any adjustments needed.
What FPS does RTX 4090 get in Pathologic 2 at 1440p?
The RTX 4090 averages approximately 125 FPS in Pathologic 2 at 1440p High settings — verdict: SMOOTH. Excellent result for high-refresh-rate 1440p monitors.
Can RTX 4090 run Pathologic 2 at 4K?
The RTX 4090 averages approximately 83 FPS in Pathologic 2 at 4K High settings — verdict: SMOOTH. 4K gaming is fully viable on this GPU for this title.
About Pathologic 2
Pathologic 2 is a reimagining of the original, focused on the Haruspex, Artemy Burakh. You return to your plague-stricken hometown as a surgeon-healer caught between local kinship traditions, colonial urban power, impossible medicine, hunger, exhaustion, and a clock that never stops. Compared with the 2005 game, it is more mechanically coherent and cinematic, but still intentionally punishing: you…
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